Because the Arduino (and Basic Stamp) are 5V devices, and most modern sensors, displays, flash cards and modes are 3.3V-only, many makers find that they need to perform level shifting/conversion to protect the 3.3V device from 5V.
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Although one can use resistors to make a divider, for high speed transfers, the resistors can add a lot of slew and cause havoc that is tough to debug. For that reason, we like using 4050/74LVX245 series and similar logic to perform proper level shifting. Only problem is that they are only good in one direction which can be a problem for some specialty bi-diectional interfaces and also makes wiring a little hairy.
That's where this lovely chip, the TXB0108 bi-directional level converter comes in! This chip perform bidirectional level shifting from pretty much any voltage to any voltage and will auto-detect the direction. Only thing that doesn't work well with this chip is i2c (because it uses strong pullups which confuse auto-direction sensor). If you need to use pullups, you can but they should be at least 50K ohm - the ones internal to AVRs/Arduino are about 100K ohm so those are OK! Its a little more luxurious than a 74LVX245 but if you just don't want to worry about directional pins this is a life saver!
This breakout saves you from having to solder the very fine pitch packages that this chip comes with. We also add 0.1uF caps onto both sides and a 10K pull-up resistor on the output enable pin so you can use it right out of the box!